BDBM50196630 CHEMBL3942452::US10167270, Compound 8d

SMILES C(CNc1nc(nc2ccccc12)-c1cccnc1)Cc1ccccc1

InChI Key InChIKey=KNPAHIAFSKZRIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50196630   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50196630(CHEMBL3942452 | US10167270, Compound 8d)
Affinity DataIC50:  1.53E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed