BDBM50212258 GS-4997::Selonsertib

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2cc(c(C)cc2F)-n2cnc(c2)C2CC2)n1

InChI Key InChIKey=YIDDLAAKOYYGJG-UHFFFAOYSA-N

Data  15 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212258   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California

Curated by ChEMBL

LigandBDBM50212258(GS-4997 | Selonsertib)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:Inhibition of ASK1 (unknown origin) using biotin-MBP as substrate after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI