BDBM50354833 AGF94::CHEMBL1834488

SMILES Nc1nc2[nH]c(CCCc3ccc(s3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=WMBYSCVMFMNUQV-LBPRGKRZSA-N

Data  6 KI  23 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354833   

TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM50354833(AGF94 | CHEMBL1834488)
Affinity DataIC50:  68nMpH: 7.5Assay Description:GARFTase activity was determined by measuring the rate of 5,8-dideazatetrahydrofolate production in the presence of varying concentrations of antifol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed