BDBM100733 US10189794, Compound I-223::US10618902, Compound I-223::US10774052, Compound I-223::US9695132, I-223

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(N[C@@H]3CCCC[C@@H]3NC(=O)C=C)nc2n(C)c1=O

InChI Key InChIKey=JWKFJIHXPCRHPC-JKSUJKDBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100733   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM100733(US10189794, Compound I-223 | US10618902, Compound ...)
Affinity DataIC50: <500nMAssay Description:A 10× stock solution of FGFR4-WT (PR4380C or P3054), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 10, was prepared as descr...More data for this Ligand-Target Pair
In DepthDetails US Patent