BDBM299489 N-[3-(4-amino- quinazolin-6-yl) phenyl]-2-(2- oxopyrrolidin- 1-yl)acetamide::US9592235, Example 262::US9855269, Compound 109
SMILES Nc1ncnc2ccc(cc12)-c1cccc(NC(=O)CN2CCCC2=O)c1
InChI Key InChIKey=NZEJGWLLOLNGHH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 299489
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 328nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair