BDBM377145 N-{4-[(3S)-3-Aminopiperidin-1-yl]quinolin-3-yl}-2-(2,6-difluorophenyl)-1,3-thiazole-4-carboxamide::US10265307, Example 2::US10517858, Example 2::US10828290, Example 2::US11229631, Example 2
SMILES N[C@H]1CCCN(C1)c1c(NC(=O)c2csc(n2)-c2c(F)cccc2F)cnc2ccccc12
InChI Key InChIKey=MUEQZLBFVXWRSM-AWEZNQCLSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 377145
Affinity DataIC50: >40nMAssay Description:Pim-1 and Pim-3 kinase assays20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Pim-1 and Pim-3 kinase assays20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...More data for this Ligand-Target Pair
Affinity DataIC50: >40nMAssay Description:Pim-1 and Pim-3 kinase assays20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...More data for this Ligand-Target Pair