BDBM50112133 CHEMBL3609861::US9464044, 71
SMILES CC(C)(NS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
InChI Key InChIKey=UBAPBKDXKUTATP-ZWRMXLCRSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50112133
Affinity DataIC50: 0.600nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair