BDBM50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax
SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
InChI Key InChIKey=KQKPFRSPSRPDEB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50005835
Affinity DataKi: 230nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 1A receptor in AK cells transfected with human 5-HT1A gene labeled with [3H]-8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:In vitro affinity at human cloned 5-hydroxytryptamine 1A receptor by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
Affinity DataKi: 341nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1A receptor from cloned Human membranes.More data for this Ligand-Target Pair
Affinity DataKi: 341nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1A receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
Affinity DataKi: 407nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Binding affinity towards cloned human 5-hydroxy tryptamine 1A (5-HT1A) receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1A receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Binding affinity of the compound was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Binding activity radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Ability to bind to 5-hydroxytryptamine 1A receptor from cloned human expressed in Ha7 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Binding activity radioligand.More data for this Ligand-Target Pair
Affinity DataKd: 3.16E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair