BDBM194819 US9206167, 41::USRE48059, Compound of Example 41

SMILES Cn1ccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2c1=O

InChI Key InChIKey=FQLPASRHPPCIMN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194819   

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM194819(US9206167, 41 | USRE48059, Compound of Example 41)
Affinity DataKi:  3.20nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM194819(US9206167, 41 | USRE48059, Compound of Example 41)
Affinity DataKi:  3.20nM ΔG°:  -12.0kcal/molepH: 7.4 T: 37°CAssay Description:The assay was performed according to the method by Leysen J E et al. (Leysen J E, Niemegeers C J E, Van Nueten J M and Laduron P M. [3H] Ketanserin (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent