BDBM330279 1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)- 3-(4-((2-(o-tolylamino)pyrimidin-4-yl)oxy) naphthalen-1-yl)urea::US10238658, Example 21::US10813932, Example 21::US9724347, Example 21::US9993478, Example 21

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccccc3C)n2)c2ccccc12)C(C)(C)C

InChI Key InChIKey=IHAAICCNNPXTHZ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330279   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
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US Patent
LigandPNGBDBM330279(1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)- 3-...)
Affinity DataIC50:  33nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by determining the lev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent