BDBM9274 CHEMBL1822893::US8835436, Example 8

SMILES Cc1nc(C(=O)NCCN2CCN(CC2)c2cccc(Cl)c2Cl)c(C)n1-c1ccccc1

InChI Key InChIKey=QDRMTYQLXZSORG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9274   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)
Affinity DataIC50:  31nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM9274(CHEMBL1822893 | US8835436, Example 8)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed