BDBM379634 US9926281, Compound 152

SMILES C[C@H]1CN(CCN1c1cccc(Cl)c1)C(=O)CCC1(NC(=O)NC1=O)C1CC1

InChI Key InChIKey=IABWDXKLHPEEBX-SZQRVLIRSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379634   

TargetADAMTS5(Rattus norvegicus (Rat))
Galapagos

US Patent
LigandPNGBDBM379634(US9926281, Compound 152)
Affinity DataIC50:  62nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent