BDBM474221 8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2-[(3-fluoropyridin-2-yl)methyl]-[l,2,4]triazolo [1,5-c]pyrimidin-5-amine::US10858365, Compound 1::US11629147, Cmpd. 1
SMILES Cn1cc(ccc1=O)-c1c(nc(N)n2nc(Cc3ncccc3F)nc12)-c1ccc(F)cc1
InChI Key InChIKey=CUMVKGYWZJOYNO-UHFFFAOYSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 474221
Affinity DataIC50: 2.87E+3nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+3nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair