BDBM50044675 CHEMBL3353354::US10358436, Example A56::US9907800, Example A56

SMILES O=C1Nc2ccccc2[C@]11C[C@H]1c1ccc2c(\C=C\c3ccc(CN4CCOCC4)cc3)n[nH]c2c1

InChI Key

Data  27 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50044675   

TargetAurora kinase B(Human)
University Health Network

US Patent
LigandPNGBDBM50044675(CHEMBL3353354 | US10358436, Example A56 | US990780...)
Affinity DataIC50: <100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAurora kinase B(Human)
University Health Network

US Patent
LigandPNGBDBM50044675(CHEMBL3353354 | US10358436, Example A56 | US990780...)
Affinity DataIC50: <100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAurora kinase B(Human)
University Health Network

US Patent
LigandPNGBDBM50044675(CHEMBL3353354 | US10358436, Example A56 | US990780...)
Affinity DataIC50: <100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAurora kinase B(Human)
University Health Network

US Patent
LigandPNGBDBM50044675(CHEMBL3353354 | US10358436, Example A56 | US990780...)
Affinity DataIC50: <100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAurora kinase B(Human)
University Health Network

US Patent
LigandPNGBDBM50044675(CHEMBL3353354 | US10358436, Example A56 | US990780...)
Affinity DataIC50:  49nMAssay Description:Inhibition of AURKB (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed