BDBM50213110 (R,S)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)ethylamino]ethyl}-1,3-benzenediol::CHEMBL229614::US10617654, Compound (R,S)-5::US9492405, (R,S)-5::US9492405, 37
SMILES C[C@@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
InChI Key InChIKey=QGUPDXLZKDANGO-QKKBWIMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50213110
Affinity DataKi: 340nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 341nM ΔG°: -8.20kcal/molepH: 7.8 T: 4°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Affinity DataKi: 3.41E+5nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
Affinity DataEC50: 103nMAssay Description:Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...More data for this Ligand-Target Pair
Affinity DataKd: 339nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19nMT: 37°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
Affinity DataKd: 339nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...More data for this Ligand-Target Pair