BDBM50367298 Cardene::NICARDIPINE

SMILES COC(=O)C1C(C(C(=O)OCCN(C)Cc2ccccc2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=OEIGWXLWQNTHHG-UHFFFAOYSA-N

Data  6 KI  22 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50367298   

TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50367298(Cardene | NICARDIPINE)
Affinity DataIC50:  2.00E+4nMAssay Description:Compound was tested for the inhibition of beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50367298(Cardene | NICARDIPINE)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against Beta-lactamase from DMSO stock was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50367298(Cardene | NICARDIPINE)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against Amp C beta-LactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed