BDBM453275 BDBM453327::US10730826, Compound 1a-non-racemic::US10730826, Compound 1a-racemic::US11325884, Compound 1

SMILES NCCCC[C@H](NC(=O)C1CCCC1)C(=O)COc1c(F)ccc(F)c1F

InChI Key InChIKey=OLIMBXKACVCIMM-HNNXBMFYSA-N

Data  25 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453275   

TargetCathepsin L2(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
Affinity DataIC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453275(BDBM453327 | US10730826, Compound 1a-non-racemic |...)
Affinity DataIC50: >1.00E+4nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent