BDBM50452359 CHEMBL4205073

SMILES CCOc1cc(\C=C\C(=O)c2ccncc2)cc(OC)c1OC

InChI Key InChIKey=AMVOCAFZNUMROI-UHFFFAOYSA-N

Data  14 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452359   

TargetCytochrome P450 2D6(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50452359(CHEMBL4205073)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in HEK293 cells using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate pretreated for 30 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50452359(CHEMBL4205073)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human CYP2D6 expressed in yeast microsomal membranes using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate measured after 10 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed