BDBM50572808 Gdc-9545::Giredestrant::RO-7197597::RO7197597
SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cc(NC2CN(CCCF)C2)cc1F
InChI Key InChIKey=GQCXHIKRWBIQMD-AKJBCIBTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50572808
Affinity DataIC50: 6.50E+3nMAssay Description:Reversible inhibition of CYP3A4 in human liver microsomes at 10 uM using midazolam as substrate preincubated for 10 mins followed by NADPH addition b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Reversible inhibition of CYP3A4 in human liver microsomes using testosterone as substrate preincubated for 10 mins followed by NADPH addition by LC/M...More data for this Ligand-Target Pair