BDBM50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine
SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
InChI Key InChIKey=QZUDBNBUXVUHMW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 64 hits for monomerid = 50001884
Affinity DataKi: 7.27nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity of [3H]-spiperone towards cloned mammalian Dopamine receptor D4 expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity towards human dopamine D4 receptor was determined via standard competitive displacement assays using [3H]-YM 09151 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity towards human Dopamine receptor D4.2 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity towards cloned human Dopamine receptor D4 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D4 expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Ability to displace [3H]-spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK-293 cells.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:compound was tested for its affinity to displace [3H]-spiperone cloned human Dopamine receptor D4 stably expressed in HEK-393 cell linesMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D4 expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-YM-09151-2 from human Dopamine receptor D4.2 expressed in baculovirus Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Ability to displace [3H]spiperone from dopamine receptor D4.4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO-K1 cells assessed as inhibition constant measured after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity evaluated for the displacement of [3H]spiperone against human dopamine receptor D4More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity against human dopamine receptor D4.4 using radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro binding affinity for Dopamine receptor D4More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Ability to displace [3H]-spiperone from cloned human Dopamine receptor D4 expressed in CHO K-1 cells in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to recombinant human dopamine receptor D4 expressed in CHO cells by displacement of [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Competitive binding affinity against human Dopamine receptor D4 by displacing [3H]spiperone from CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]methylspiperone from human dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]methylspiperone from human recombinant D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity at human Dopamine receptor D4 by [3H]- YM 09151 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]-YM09151-2 from human cloned dopamine D4 receptor expressed in insect Sf9 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Ability to inhibit the binding of [3H]spiperone to the Dopamine receptor D4 in COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28.4nMAssay Description:In vitro ability to inhibit [3H]-spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Binding affinity of [3H]-YM-09151 towards cloned mammalian Dopamine receptor D4 expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]-YM-09151-2 (0.06 nM) from human Dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:In vitro binding affinity at human Dopamine receptor D4.4 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 30.4nMAssay Description:In vitro ability to inhibit [3H]-6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity of [3H]-Spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Binding affinity measured at the Dopamine receptor D4 by the inhibition of [3H]-spiperone binding to human recombinant CHO cells using unlabeled halo...More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Binding affinity to Human Dopamine receptor D4 expressed in CHO cells was determined using [3H]- nemonapride as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]spiperone from human dopamine D4.4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity towards human dopamine-4.2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity towards human dopamine receptor D4More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to cloned human dopamine receptor D4 using apomorphine induced climbing test in male Swiss m...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:In vitro ability to inhibit the binding of [3H]-spiperone to cloned human dopamine receptor D4 using apomorphine induced climbing test in male Swiss ...More data for this Ligand-Target Pair