BDBM471847 (5R)-5-[3-[4-(4- chloro-3-ethoxy- 5-methoxy- phenyl) piperazin-1- yl]-3-oxo-propyl]- 5-methyl- imidazolidine- 2,4-dione::US10829478, Compound 79

SMILES CCOc1cc(cc(OC)c1Cl)N1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O

InChI Key InChIKey=QRUIBNLRDWVROJ-HXUWFJFHSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471847   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM471847((5R)-5-[3-[4-(4- chloro-3-ethoxy- 5-methoxy- pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:TABLE XI: The basis for the assay is the cleavage of the substrate 5FAM-LAQAVRSSSRK-5TAMRA (SEQ ID NO: 3) (Anaspec, custom 34891) by human TACE (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent