BDBM471847 (5R)-5-[3-[4-(4- chloro-3-ethoxy- 5-methoxy- phenyl) piperazin-1- yl]-3-oxo-propyl]- 5-methyl- imidazolidine- 2,4-dione::US10829478, Compound 79
SMILES CCOc1cc(cc(OC)c1Cl)N1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O
InChI Key InChIKey=QRUIBNLRDWVROJ-HXUWFJFHSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 471847
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:TABLE XI: The basis for the assay is the cleavage of the substrate 5FAM-LAQAVRSSSRK-5TAMRA (SEQ ID NO: 3) (Anaspec, custom 34891) by human TACE (R&D ...More data for this Ligand-Target Pair