BDBM50098512 4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxylic acid amide::CHEMBL267678

SMILES Cc1ccc(Sc2cncc3sc(cc23)C(N)=O)cc1

InChI Key InChIKey=QQGWEXFLMJGCAL-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50098512   

TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50:  20nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Selectin E expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098512(4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50:  2.50E+4nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Selectin E expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed