BDBM50528539 CHEMBL4553037

SMILES C[C@H]1CN(Cc2cc(ccc12)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1cnc(C)c1)c1cncnc1

InChI Key InChIKey=CMJJZRAAQMUAFH-INIZCTEOSA-N

Data  11 IC50  16 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50528539   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50528539(CHEMBL4553037)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of human recombinant GST-tagged DDR1 (440 to 876 residues) expressed in baculovirus infected Sf9 insect cells using fluorescein-poly GAT a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50528539(CHEMBL4553037)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to wild type human partial length DDR1 (565 to 876 residues) expressed in bacterial expression system preincubated for 1 hr measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50528539(CHEMBL4553037)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to wild type human partial length DDR1 (565 to 876 residues) expressed in bacterial expression system preincubated for 1 hr measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50528539(CHEMBL4553037)
Affinity DataIC50:  15nMAssay Description:Inhibition of GST-tagged recombinant human DDR1 (440 to 876 amino acids) expressed in baculovirus using fluorescein-poly GAT as substrate after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50528539(CHEMBL4553037)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of human recombinant GST-tagged DDR1 (440 to 876 residues) expressed in baculovirus infected Sf9 insect cells using fluorescein-poly GAT a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed