BDBM287011 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-((2,2,2-trifluoroethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one::US10294223, Cpd No. 55::US11078199, Cpd 55::US9567334, Example 55::US9815834, Compound 55
SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(NCC(F)(F)F)nc2n(CCCN2CCN(CC2)C(=O)C=C)c1=O
InChI Key InChIKey=JXMYXVQTSAHUJU-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 287011
Affinity DataIC50: 16.1nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair