BDBM50557569 CHEMBL4759798

SMILES Nc1nc2sc(CCCc3csc(c3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=QXWUFUZJYLBZQF-LBPRGKRZSA-N

Data  1 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50557569   

TargetFolate receptor beta(Homo sapiens (Human))
Wayne State University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50557569(CHEMBL4759798)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of human FRbeta expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTiter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed