BDBM50466038 CHEMBL4281823

SMILES CCn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc12

InChI Key InChIKey=APPXQUDJLJXULP-UHFFFAOYSA-N

Data  49 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466038   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50:  92nMAssay Description:Inhibition of recombinant human Met A1209G/V1290L double mutant (974 to end residues) using KKKGQEEEYVFIE as substrate after 40 mins in presence of [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed