BDBM50158610 (4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-methanone::CHEMBL555146

SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(F)cc1

InChI Key InChIKey=VGSYEFOBFMUWGO-OAHLLOKOSA-N

Data  40 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158610   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158610((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...)
Affinity DataKi:  0.270nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158610((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158610((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed