BDBM50252395 CHEMBL4087616

SMILES CN1C(=O)C2CN(Cc3c2c2ccccc2n3Cc2ccc(cc2)C(=O)NO)C1=O

InChI Key InChIKey=ZCAIUGLOTHAUQX-UHFFFAOYSA-N

Data  10 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252395   

TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50252395(CHEMBL4087616)
Affinity DataKi:  0.700nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus-infected Sf9 insect cells using RHKK(Ac)AMC as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50252395(CHEMBL4087616)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50252395(CHEMBL4087616)
Affinity DataIC50:  4nMAssay Description:Inhibition of human HDAC6 using RHKKAc as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed