BDBM50550224 CHEMBL4797755

SMILES OC(=O)C(F)(F)F.NCc1ccc(NC(=O)N2C(CC(=O)NCCC(O)=O)CC2=O)cc1

InChI Key InChIKey=WNJSILFLYVIFJS-UHFFFAOYSA-N

Data  11 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50550224   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50550224(CHEMBL4797755)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of fibrinogen binding to alpha2bbeta3 isolated from human HEL cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50550224(CHEMBL4797755)
Affinity DataEC50:  1.56E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50550224(CHEMBL4797755)
Affinity DataIC50:  1.56E+3nMAssay Description:Antagonist activity at alpha2bbeta3 in human HEL cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed