BDBM19190 (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one::CHEMBL131::Delta-Cortef::Deltacortril::Prednisolone::US10196374, Prednisolone
SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
InChI Key InChIKey=OIGNJSKKLXVSLS-VWUMJDOOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 19190
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Displacement of TAMRA-labeled dexamethasone from mineralocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00200nMAssay Description:Agonist activity at human mineralocorticoid receptor expressed in human A549 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant mineralocorticoid receptor expressed in baculovirus infected insect...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Binding affinity to mineralocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by flu...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at mineralocorticoid receptor in human A549 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of 3H-aldosterone from MR (unknown origin) ligand binding domain by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-aldosterone from human mineralocorticoid receptor LBD (729 to 984 residues) after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair