BDBM130909 US10683289, Example Staurosporine::US10927120, Compound staurosporine::US8822500, Stauro- sporine::US9920060, Staurosporine

SMILES CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13

InChI Key InChIKey=HKSZLNNOFSGOKW-UHFFFAOYSA-N

Data  13 IC50

PDB links: 89 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130909   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent

LigandBDBM130909(US10683289, Example Staurosporine | US10927120, Co...)Copy SMILESCopy InChI

Affinity DataIC50:  55nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue # PV4011), ATP was purchased from Sigma (Catalogue # A7699), HTRF® KinEASE™ Assay System was obtained...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In DepthDetails US Patent
PDB3D Structure (crystal)
Copy BDB DOI