BDBM50212258 GS-4997::Selonsertib

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2cc(c(C)cc2F)-n2cnc(c2)C2CC2)n1

InChI Key InChIKey=YIDDLAAKOYYGJG-UHFFFAOYSA-N

Data  15 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212258   

TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL

LigandBDBM50212258(GS-4997 | Selonsertib)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI