BDBM39341 11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one::11-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;hydrochloride::11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;hydrochloride::11-[2-(4-methylpiperazin-1-yl)ethanoyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;hydrochloride::11-[2-(4-methylpiperazino)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;hydrochloride::CHEMBL9967::MLS000069702::PIRENZEPINE::PIRENZEPINE DIHYDROCHLORIDE::SMR000058502::cid_185248
SMILES CN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc23)CC1
InChI Key InChIKey=RMHMFHUVIITRHF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 65 hits for monomerid = 39341
Affinity DataKi: 60nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:In vitro inhibition of [3H]QNB binding to Muscarinic receptor from rat cortical homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 322nMAssay Description:In vitro inhibition of [3H]OXO-M binding to Muscarinic receptor from rat cortical homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:In vitro displacement of [3H]quinuclidinyl benzilate (QNB) from rat cerebral cortex muscarinic receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 322nMAssay Description:In vitro ability to displace [3H]oxotremorine-M (OXO-M) from rat cerebral cortex muscarinic receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of central amygdaloid nucleus region of foreb...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of ventral dentate gyrus region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of lateral hypothalamus region of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of medial amygdaloid nucleus region of foreb...More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of lateral septal nucleus of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of inferior coliculus region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of posterior hypothalamus region of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of cerebellum, lobe 4 region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of bed nucleus stria terminalis region of mi...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of hippocampus CA3 region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of hippocampus CA1 region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of ventral subiculum region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of subiculum region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of reticular thalamic nucleus region of midbr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of lateral dorsal thalamic nucleus region of...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of medial geniculate region of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of retrosplenial cortex region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of Primary olfactory cortex region of forebra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of anterior hypothalamus region of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of neostriatum region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of reuniens thalamic nucleus region of midbr...More data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of posterior cingulate cortex region of foreb...More data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of cerebellum, lobe 2 region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of cuneiform nucleus region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of substantia nigra region of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of periaqueductal region of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of dorsal raphe nucleus region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of cerebral cortex layers VI of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of dorsal tegmentum region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of central medial thalamic nucleus region of...More data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of medial raphe nucleus region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of hippocampus CA4 region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of cudate nucleus region of forebrainMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of cerebral cortex layers IV and V of forebra...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of basolateral amygdaloid nucleus region of f...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of dorsal parabrachial nucleus region of hin...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of cerebellum, lobe 1 region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of superior coliculus region of midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of central gray, pons region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of superior coliculus, infragranular region o...More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of anterior cingulate cortex region of forebr...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of cerebellum, lobe 3 region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of raphe pontis region of hindbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of binding of [3H]l-quinuclidinyl benzilate ([3H]L-QNB) to muscarinic acetylcholine receptor of ventral lateral geniculate region of midbr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of binding of [3H]L-quinuclidinyl benzilate ([3H]-l-QNB) to muscarinic acetylcholine receptor of rhomboid thalamic nucleus region of midbr...More data for this Ligand-Target Pair