BDBM50143282 (-)-cytisine::(1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one::(1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one::(1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one::(1R,9S)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one::(1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one::1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one::1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one (cytisine)::CHEMBL497939::Cytisine1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one::cytisine
SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12
InChI Key InChIKey=ANJTVLIZGCUXLD-YGPZHTELSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50143282
Affinity DataKi: 0.900nMAssay Description:In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]-alpha-Bungarotoxin in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampusMore data for this Ligand-Target Pair
Affinity DataKi: 261nMAssay Description:Displacement of [3H]methyllycaconitine from Sprague-Dawley rat brain alpha7 nAChR after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: 331nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.42E+3nMAssay Description:Binding affinity to human Nicotinic acetylcholine receptor alpha7 expressed in IMR32 cells using [3H]alpha-bungarotoxinMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of [3H]MLA from rat alpha7 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+3nMAssay Description:Inhibition of [3H]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha7 of IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha-7 subunit in rat GH4C1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.82E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR in GH4C1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.89E+3nMAssay Description:Partial agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Binding affinity to rat alpha7 nAChRMore data for this Ligand-Target Pair
Affinity DataEC50: 7.10E+4nMAssay Description:Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
Affinity DataEC50: 7.10E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha 7 expressed in xenopus oocytesMore data for this Ligand-Target Pair