BDBM152711 4-methyl-6-[2-(3-{methyl[2-(methylamino)ethyl]amino}phenyl)ethyl]pyridin-2-amine (13)::US9951014, Name 10a

SMILES CNCCN(C)c1cccc(CCc2cc(C)cc(N)n2)c1

InChI Key InChIKey=MIKRWQRFDGLBCF-UHFFFAOYSA-N

Data  8 KI  1 Kd

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152711   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM152711(4-methyl-6-[2-(3-{methyl[2-(methylamino)ethyl]amin...)
Affinity DataKi:  5.34E+3nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM152711(4-methyl-6-[2-(3-{methyl[2-(methylamino)ethyl]amin...)
Affinity DataKi:  5.34E+3nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by oxyhemoglobin NO assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed