BDBM50240975 CHEMBL4084907

SMILES Nc1cc(c(cn1)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)C(F)(F)F

InChI Key InChIKey=ADGGYDAFIHSYFI-UHFFFAOYSA-N

Data  8 KI  16 IC50  9 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240975   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
University of Basel

Curated by ChEMBL
LigandPNGBDBM50240975(CHEMBL4084907)
Affinity DataKd:  230nMAssay Description:Binding affinity to human VPS34 (S282 to H879 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
University of Basel

Curated by ChEMBL
LigandPNGBDBM50240975(CHEMBL4084907)
Affinity DataIC50:  8.49E+3nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed