BDBM50240975 CHEMBL4084907
SMILES Nc1cc(c(cn1)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)C(F)(F)F
InChI Key InChIKey=ADGGYDAFIHSYFI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50240975
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Antagonist activity was determined against beta-1 adrenergic receptor in spontaneously beating rat atriaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant N-terminal His6-tagged PI3K p110alpha (unknown origin) incubated for 1 hr by FR...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kalpha (unknown origin) expressed in baculovirus expression system using L-alpha-phosphatidylinositol as substrate by luminescence a...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataKd: 1.5nMAssay Description:Binding affinity to human PI3Kalpha (R108 to N1068 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair