BDBM50389066 CHEMBL2064347
SMILES Cn1c(Cc2nc(cc(=O)[nH]2)N2CCOCC2)nc2c(cccc12)-c1ccccc1
InChI Key InChIKey=DAIOZRXKBOQYHF-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50389066
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research & Development
Curated by ChEMBL
Sanofi Research & Development
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research & Development
Curated by ChEMBL
Sanofi Research & Development
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair