BDBM50365890 CHEMBL1957875
SMILES C[C@@H](Nc1ccccc1)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1
InChI Key InChIKey=CPRAGQJXBLMUEL-MRXNPFEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50365890
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sanofi Research & Development
Curated by ChEMBL
Sanofi Research & Development
Curated by ChEMBL
Affinity DataIC50: 252nMAssay Description:Inhibition of human PI3Kdelta-mediated Akt phosphorylation at Ser473 residue expressed in mouse MEF-3T3 cells after 0.5 to 2 hrs by Western blot anal...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sanofi Research & Development
Curated by ChEMBL
Sanofi Research & Development
Curated by ChEMBL
Affinity DataIC50: 851nMAssay Description:Inhibition of poly-His tagged human PI3Kdelta expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as substrate p...More data for this Ligand-Target Pair