BDBM318032 2-[4-[(3-Methoxy-2- pyridyl)methyl]piperazin-1-yl]-8- methyl-3,5,6,7- tetrahydropyrido[2,3-d]pyrimidin- 4-one dihydrochloride::US9624218, Example 33

SMILES COc1cccnc1CN1CCN(CC1)c1nc2N(C)CCCc2c(=O)[nH]1

InChI Key InChIKey=SSDOGFZFEYCRRH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318032   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318032(2-[4-[(3-Methoxy-2- pyridyl)methyl]piperazin-1-yl]...)
Affinity DataIC50:  35.8nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent