BDBM318037 2-[4-[(2-Chlorophenyl)methyl]piperazin-1-yl]-8-methyl-3,5,6,7-tetrahydropyrido[2,3-d]pyrimidin-4-one::US9624218, Example 38

SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ccccc2Cl)CC1

InChI Key InChIKey=CGRPSBDSLCXTLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318037   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Eli Lilly

US Patent
LigandPNGBDBM318037(2-[4-[(2-Chlorophenyl)methyl]piperazin-1-yl]-8-met...)
Affinity DataIC50:  45.3nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent