BDBM50505333 CHEMBL4437173
SMILES CC(C)(O)c1ccc(cc1)-c1nc2c(F)cc(F)cc2c(=O)[nH]1
InChI Key InChIKey=FHBYLOWAINBPRJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50505333
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare
Curated by ChEMBL
Merck Healthcare
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human TNKS1 (1001 to 1327 end residues) expressed in Baculovirus infected Sf9 cells using biotinylate...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare
Curated by ChEMBL
Merck Healthcare
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare
Curated by ChEMBL
Merck Healthcare
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare
Curated by ChEMBL
Merck Healthcare
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair