BDBM50505333 CHEMBL4437173

SMILES CC(C)(O)c1ccc(cc1)-c1nc2c(F)cc(F)cc2c(=O)[nH]1

InChI Key InChIKey=FHBYLOWAINBPRJ-UHFFFAOYSA-N

Data  20 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50505333   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human TNKS1 (1001 to 1327 end residues) expressed in Baculovirus infected Sf9 cells using biotinylate...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)
Affinity DataIC50:  7nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)
Affinity DataIC50:  7nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)
Affinity DataIC50:  10nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair