BDBM50266869 CHEMBL4094163

SMILES Cc1cc(\C=C\C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(cc3)S(N)(=O)=O)CC2)nc2ccsc12

InChI Key InChIKey=GVCHBMCBPBRORW-ONEGZZNKSA-N

Data  17 IC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266869   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50266869(CHEMBL4094163)
Affinity DataIC50:  186nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50266869(CHEMBL4094163)
Affinity DataIC50:  180nMAssay Description:Inhibition of human ERG expressed in CHO cells by manual patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50266869(CHEMBL4094163)
Affinity DataIC50:  186nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed