BDBM50121163 3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-5'-yl)benzonitrile::3-[2'-oxospiro[cyclohexane-1,3'-(2',3'-dihydro-1'H-indole)]-5-yl]benzonitrile::CHEMBL308938
SMILES O=C1Nc2ccc(cc2C11CCCCC1)-c1cccc(c1)C#N
InChI Key InChIKey=LCGYUHWSQNIRBE-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50121163
Affinity DataIC50: 15nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphataseMore data for this Ligand-Target Pair