BDBM50022309 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine::4-butyl-1,2-diphenylpyrazolidine-3,5-dione::4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione::CHEMBL101::PHENYLBUTAZONE::Phenylbutazon

SMILES CCCCc1c(O)n(-c2ccccc2)n(-c2ccccc2)c1=O

InChI Key InChIKey=PKYKNPLSFOKASK-UHFFFAOYSA-N

Data  4 KI  8 IC50  1 EC50

PDB links: 5 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022309   

TargetProstaglandin G/H synthase 1(Sheep)
Dupont Pharmaceuticals

Curated by ChEMBL

LigandBDBM50022309(3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine | 4-b...)Copy SMILESCopy InChI

Affinity DataIC50:  3.84E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoChEBI
CHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50022309(3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine | 4-b...)Copy SMILESCopy InChI

Affinity DataIC50:  3.00E+3nMAssay Description:Compound was evaluated for inhibition of Prostaglandin G/H synthase 1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoChEBI
CHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
Copy BDB DOI