BDBM13382 3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy]methyl}benzonitrile::A313326 Analogue 18::CHEMBL158553

SMILES Cn1cncc1C(OCc1ccc(cc1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=RGXWUSMPBUPQSB-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13382   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
The M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM13382(3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1-methyl-1H...)
Affinity DataIC50:  871nMAssay Description:Inhibition of FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13382(3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1-methyl-1H...)
Affinity DataEC50:  5.20nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed