BDBM50240780 CHEMBL4062877
SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)ccc1O
InChI Key InChIKey=QXIOZIFTPMAING-VWLOTQADSA-N
Data 37 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50240780
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of CCDC6-fused RET (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of cell proliferation after 72 hrs by cell count...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant Ret (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair