BDBM50333373 CHEMBL1645462::[4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamino]-5-methyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid

SMILES Cc1c(NC(=O)OC[C@@H]2COCCN2)cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12

InChI Key InChIKey=LUJZZYWHBDHDQX-QFIPXVFZSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333373   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333373(CHEMBL1645462 | [4-[[1-(3-fluorophenyl)methyl]-1H-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333373(CHEMBL1645462 | [4-[[1-(3-fluorophenyl)methyl]-1H-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed