BDBM98678 US8497286, 154

SMILES CCOC[C@@H](CC(C)C)NC(=O)[C@@H]1CNC[C@@H]([C@@H]1O)C(=O)N(C1CC1)c1ccc(cn1)C(C)C

InChI Key InChIKey=YOVGCKBDPOHLAV-CNIHBODFSA-N

Data  16 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98678   

TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98678(US8497286, 154)
Affinity DataIC50:  2nMAssay Description:Inhibition activity of renin using FRET assay.More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98678(US8497286, 154)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98678(US8497286, 154)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant renin using fluorescence-quenched RE(EDANS)IHPFHLVIHTK(Dabcyl)R substrate by fluorimetric assayMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98678(US8497286, 154)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant renin in presence of human plasma using Ac- IHPFHL-VIHNK-(DY-505-X5)-COOH substrate by fluorimetric assayMore data for this Ligand-Target Pair