BDBM379329 N2-(1H-benzo[d]imidazol-6-yl)-N4-cyclopropyl-5-(trifluoromethyl)pyrimidine-2,4-diamine::US10266549, Example 211::US10774092, Example 211

SMILES FC(F)(F)c1cnc(Nc2ccc3nc[nH]c3c2)nc1NC1CC1

InChI Key InChIKey=HTSMUTPVZNMYSW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 379329   

TargetSerine/threonine-protein kinase ULK2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM379329(N2-(1H-benzo[d]imidazol-6-yl)-N4-cyclopropyl-5-(tr...)
Affinity DataIC50:  703nMAssay Description:Inhibition of ULK2 (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase ULK2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM379329(N2-(1H-benzo[d]imidazol-6-yl)-N4-cyclopropyl-5-(tr...)
Affinity DataIC50:  720nMAssay Description:Inhibition of recombinant human ULK2 (1 to 478 residues) expressed in Sf9 cells using myelin basic protein as substrate by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed